Category Archives: Hematology
An investigation combining drugs and endogenous substances to treat leukemia
The treatment is active against leukemia cells without causing adverse effects on healthy cells. An expert group Molecular Immunology Group at the University of Granada (UGR) is checking the effectiveness of a combination of drugs and substances produced by the body that act against the cells affected by leukemia, without causing adverse effects on healthy [...]
An investigation identified the mechanisms of expansion of the leukemic cells
The survey, conducted by the CSIC, defines a potential strategy for the design of future treatments for disease. A team at the Consejo Superior de Investigaciones Científicas (CSIC) has discovered the mechanism by which the enzyme MMP-9 affects the survival of cells of B chronic lymphocytic leukemia (CLL-B) and allows the spread of the disease. [...]
The transplantation of peripheral blood, as effective as bone marrow
Hematopoietic stem cell transplantation has been consolidated in recent years as a good alternative to traditional bone marrow transplantation. This method allows cells in the bloodstream of a compatible donor, able to repopulate the bone marrow of a patient with leukemia, more simply and without anesthesia. A study published in the journal ‘The Lancet’ after [...]
Different way to eliminate leukemia stem cells
A new molecular tool could become a therapeutic option for acute myeloid leukemia. According to a study published in the latest issue of Cell Stem Cell, preclinical studies conducted by a team from Children Cancer Institute Australia have demonstrated that CD123 molecule is over expressed in leukemia stem cells, whereas its expression in healthy cells [...]
Stem cells for severe sickle cell anemia
U.S. scientists published in The New England Journal of Medicine have succeeded in reversing the disease in 9 of 10 patients treated with a new procedure. The preliminary study results show that the “mini” stem cells could reverse the severe sickle cell anemia in adults, according to a study by the NIH and Johns Hopkins [...]