Category Archives: Hematology

An investigation identified the mechanisms of expansion of the leukemic cells

The survey, conducted by the CSIC, defines a potential strategy for the design of future treatments for disease.
A team at the Consejo Superior de Investigaciones Científicas (CSIC) has discovered the mechanism by which the enzyme MMP-9 affects the survival of cells of B chronic lymphocytic leukemia (CLL-B) and allows the spread of the disease.
The finding, [...]

The transplantation of peripheral blood, as effective as bone marrow

Hematopoietic stem cell transplantation has been consolidated in recent years as a good alternative to traditional bone marrow transplantation. This method allows cells in the bloodstream of a compatible donor, able to repopulate the bone marrow of a patient with leukemia, more simply and without anesthesia. A study published in the journal ‘The Lancet’ after [...]

Different way to eliminate leukemia stem cells

A new molecular tool could become a therapeutic option for acute myeloid leukemia.
According to a study published in the latest issue of Cell Stem Cell, preclinical studies conducted by a team from Children Cancer Institute Australia have demonstrated that CD123 molecule is over expressed in leukemia stem cells, whereas its expression in healthy cells is [...]

Stem cells for severe sickle cell anemia

U.S. scientists published in The New England Journal of Medicine have succeeded in reversing the disease in 9 of 10 patients treated with a new procedure.
The preliminary study results show that the “mini” stem cells could reverse the severe sickle cell anemia in adults, according to a study by the NIH and Johns Hopkins University [...]

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